Molecular and Clinical Characteristics of Tricarboxylic Acid Cycle-associated Tumors
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چکیده
منابع مشابه
Tricarboxylic acid cycle dysfunction as a cause of human diseases and tumor formation.
A renewed interest in tricarboxylic acid cycle enzymopathies has resulted from the report that, in addition to devastating encephalopathies, these can result in various types of tumors in human. We first review the major features of the cycle that may underlie this surprising variety of clinical features. After discussing the rare cases of encephalopathies associated with specific deficiencies ...
متن کاملInvited Review Tricarboxylic acid cycle dysfunction as a cause of human diseases and tumor formation
Brière, Jean-Jacques, Judith Favier, Anne-Paule Gimenez-Roqueplo, and Pierre Rustin. Tricarboxylic acid cycle dysfunction as a cause of human diseases and tumor formation. Am J Physiol Cell Physiol 291: C1114–C1120, 2006. First published June 7, 2006; doi:10.1152/ajpcell.00216.2006.—A renewed interest in tricarboxylic acid cycle enzymopathies has resulted from the report that, in addition to de...
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Objective(s):Higher cellular reactive oxygen species (ROS) levels is important in reducing cellular energy charge (EC) by increasing the levels of key metabolic protein, and nitrosative modifications, and have been shown to damage the cardiac tissue of diabetic mice. However, the relation between energy production and heart function is unclear. Materials and Methods:Streptozotocin (STZ, 150 mg...
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Background: One of the main sunfl ower diseases is the white mold Sclerotinia sclerotiorum. The oxalic acid (OA), which is one of the main pathogenicity factors of this fungus, beside the direct toxicity on the host, has other functions such as the disruption of the cell wall and chelating out the calcium ions.Objectives: Regarding the importance of this disease, it is im...
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تاریخ انتشار 2008